CAS NO. |
|
M. F. | C22H18N4OS |
M.W. | 386.4695 |
InChl | InChI=1/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+ |
Application | |
Application | Axitinib (AG013736; trade name Inlyta) is a small molecule tyrosine kinase inhibitor developed by Pfizer. It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models and has shown partial responses in clinical trials with renal cell carcinoma (RCC) and several other tumour types.Hot tags: Zolmitriptan . It was approved for RCC by the U.S. Food and Drug Administration after showing a modest increase in progression-free survival, though there have been reports of fatal adverse effects. |
Biophysical-chemical information | |
Density | 1.35g/cm3 |
Boiling Point | 668.9°C at 760 mmHg |
Refractive Index | 1.728 |
Flash Point | 358.3°C |
Vapour Pressur | 9.35E-18mmHg at 25°C |
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